Title : Phenethyl isothiocyanate, by virtue of its antioxidant activity, inhibits invasiveness and metastatic potential of breast cancer cells: HIF-1α as a putative target.

Pub. Date : 2016

PMID : 26480821






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 PEITC-induced nuclear accumulation of Nrf2, increased the activities of several antioxidant enzymes, and thus reduced the ROS burden of the tumor cells by acting as an indirect antioxidant. phenethyl isothiocyanate NFE2 like bZIP transcription factor 2 Homo sapiens
2 A probable link between down-regulation of HIF-1alpha with reduction of ROS by PEITC through induction of Nrf2 was determined. phenethyl isothiocyanate NFE2 like bZIP transcription factor 2 Homo sapiens