Title : High constitutive Akt2 activity in U937 promonocytes: effective reduction of Akt2 phosphorylation by the histamine H2-receptor and the β2-adrenergic receptor.

Pub. Date : 2016 Jan

PMID : 26475619






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1 In our present study, we evaluated the pharmacological profile of the H2R and the beta2AR regarding Akt2 phosphorylation at Ser474 via western blot analysis and ELISA and cAMP accumulation via HPLC-MS/MS in U937 promonocytes. Cyclic AMP adrenoceptor beta 2 Homo sapiens