Title : Saponarin activates AMPK in a calcium-dependent manner and suppresses gluconeogenesis and increases glucose uptake via phosphorylation of CRTC2 and HDAC5.

Pub. Date : 2015 Nov 15

PMID : 26471090






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This nuclear translocation was inhibited by increased phosphorylation of CRTC2 and HDAC5 by saponarin-induced AMPK in HepG2 cells and suppression of CREB and FoxO1 transactivation activities in cells stimulated by saponarin. saponarin cAMP responsive element binding protein 1 Homo sapiens
2 This nuclear translocation was inhibited by increased phosphorylation of CRTC2 and HDAC5 by saponarin-induced AMPK in HepG2 cells and suppression of CREB and FoxO1 transactivation activities in cells stimulated by saponarin. saponarin cAMP responsive element binding protein 1 Homo sapiens