Title : Alpha lipoic acid inhibits proliferation and epithelial mesenchymal transition of thyroid cancer cells.

Pub. Date : 2016 Jan 5

PMID : 26463583






6 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Recent studies suggested the possibility of ALA as a potential anti-cancer agent, because it could activate adenosine monophosphate activated protein kinase (AMPK) and inhibit transforming growth factor-beta (TGFbeta) pathway. Thioctic Acid transforming growth factor beta 1 Homo sapiens
2 Recent studies suggested the possibility of ALA as a potential anti-cancer agent, because it could activate adenosine monophosphate activated protein kinase (AMPK) and inhibit transforming growth factor-beta (TGFbeta) pathway. Thioctic Acid transforming growth factor beta 1 Homo sapiens
3 ALA suppressed TGFbeta production and inhibited induction of p-Smad2 and twist by TGFbeta1 or TGFbeta2. Thioctic Acid transforming growth factor beta 1 Homo sapiens
4 ALA suppressed TGFbeta production and inhibited induction of p-Smad2 and twist by TGFbeta1 or TGFbeta2. Thioctic Acid transforming growth factor beta 1 Homo sapiens
5 These findings indicate that ALA reduces cancer cell migration and invasion through suppression of TGFbeta production and inhibition of TGFbeta signaling pathways in thyroid cancer cells. Thioctic Acid transforming growth factor beta 1 Homo sapiens
6 These findings indicate that ALA reduces cancer cell migration and invasion through suppression of TGFbeta production and inhibition of TGFbeta signaling pathways in thyroid cancer cells. Thioctic Acid transforming growth factor beta 1 Homo sapiens