Title : Disulfide Sensitivity in the Env Protein Underlies Lytic Inactivation of HIV-1 by Peptide Triazole Thiols.

Pub. Date : 2015 Dec 18

PMID : 26458166






2 Functional Relationships(s)
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1 Inhibition of lysis by gp120 mAb 2G12, which binds at the base of the V3 loop, as well as disulfide mutational effects, argued that PTT-induced disruption of the gp120 disulfide cluster at the base of the V3 loop is an important step in lytic inactivation of HIV-1. Bialaphos Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1
2 Inhibition of lysis by gp120 mAb 2G12, which binds at the base of the V3 loop, as well as disulfide mutational effects, argued that PTT-induced disruption of the gp120 disulfide cluster at the base of the V3 loop is an important step in lytic inactivation of HIV-1. Bialaphos Envelope surface glycoprotein gp160, precursor Human immunodeficiency virus 1