Title : Different effects of resveratrol on early and late passage mesenchymal stem cells through β-catenin regulation.

Pub. Date : 2015 Nov 27

PMID : 26456654






2 Functional Relationships(s)
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Protein Name
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1 In early passage MSCs expressing SIRT1, resveratrol decreased ERK and GSK-3beta phosphorylation, suppressing beta-catenin activity. Resveratrol glycogen synthase kinase 3 beta Homo sapiens
2 In contrast, in late passage MSCs, which did not express SIRT1, resveratrol increased ERK and GSK-3beta phosphorylation, activating beta-catenin. Resveratrol glycogen synthase kinase 3 beta Homo sapiens