Title : Fetal Val108/158Met catechol-O-methyltransferase (COMT) polymorphism and placental COMT activity are associated with the development of preeclampsia.

Pub. Date : 2016 Jan

PMID : 26450530






1 Functional Relationships(s)
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1 However, the preeclamptic patients had elevated homocysteine levels that correlated inversely with 2-ME, indicating that an altered methionine-homocysteine metabolism may contribute to reduce COMT activity in vivo and explain the decreased levels of 2-ME in preeclamptic women. Methionine catechol-O-methyltransferase Homo sapiens