Pub. Date : 2016 Feb
PMID : 26450510
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Proteins involved in glycolysis, acetate metabolism, fatty acid synthesis, TCA cycle, glyoxylate cycle, the pentose phosphate pathway, respiration, transportation, and stress response were found to be upregulated in faa1 faa4 [Acot5s] as compared to the wild type. | Fatty Acids | long-chain fatty acid-CoA ligase FAA1 | Saccharomyces cerevisiae S288C |
| 2 | Taken together with our metabolite analysis, our results showed that the disruption of Faa1 and Faa4 and expression of Acot5s in the engineered strain faa1 faa4 [Acot5s] not only relieved the feedback inhibition of fatty acyl-CoAs on fatty acid synthesis, but also caused a major metabolic rearrangement. | Fatty Acids | long-chain fatty acid-CoA ligase FAA1 | Saccharomyces cerevisiae S288C |
| 3 | Taken together with our metabolite analysis, our results showed that the disruption of Faa1 and Faa4 and expression of Acot5s in the engineered strain faa1 faa4 [Acot5s] not only relieved the feedback inhibition of fatty acyl-CoAs on fatty acid synthesis, but also caused a major metabolic rearrangement. | Fatty Acids | long-chain fatty acid-CoA ligase FAA1 | Saccharomyces cerevisiae S288C |