Protein Name long-chain fatty acid-CoA ligase FAA1
Organism Saccharomyces cerevisiae S288C
Gene ID 854495
Gene Symbol

FAA1

UniProt P30624 (LCF1_YEAST)
Relationships Total Number of functionally related compound(s) : 37
Total Number of Articles : 34
Description

long-chain fatty acid-CoA ligase FAA1

Gene Summary

Enables long-chain fatty acid-CoA ligase activity and medium-chain fatty acid-CoA ligase activity. Involved in long-chain fatty acid import into cell; long-chain fatty-acyl-CoA metabolic process; and sphingoid long-chain base transport. Located in lipid droplet and plasma membrane. Used to study Sjogren-Larsson syndrome. Human ortholog(s) of this gene implicated in asthma; breast cancer; intellectual disability; non-syndromic X-linked intellectual disability 63; and prostate cancer. Orthologous to several human genes including ACSL4 (acyl-CoA synthetase long chain family member 4). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • long-chain fatty acid-CoA ligase FAA1
  • YOR317W
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Properties