Title : Comparative proteomic analysis of engineered Saccharomyces cerevisiae with enhanced free fatty acid accumulation.

Pub. Date : 2016 Feb

PMID : 26450510






2 Functional Relationships(s)
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1 Taken together with our metabolite analysis, our results showed that the disruption of Faa1 and Faa4 and expression of Acot5s in the engineered strain faa1 faa4 [Acot5s] not only relieved the feedback inhibition of fatty acyl-CoAs on fatty acid synthesis, but also caused a major metabolic rearrangement. Acyl Coenzyme A long-chain fatty acid-CoA ligase FAA1 Saccharomyces cerevisiae S288C
2 Taken together with our metabolite analysis, our results showed that the disruption of Faa1 and Faa4 and expression of Acot5s in the engineered strain faa1 faa4 [Acot5s] not only relieved the feedback inhibition of fatty acyl-CoAs on fatty acid synthesis, but also caused a major metabolic rearrangement. Acyl Coenzyme A long-chain fatty acid-CoA ligase FAA1 Saccharomyces cerevisiae S288C