Pub. Date : 2015 Nov 10
PMID : 26416459
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Re-expression of Atg5 restores the lipidation of LC3 and rescues DU145 and MEF atg5-/- cells from sorafenib-induced cell death. | Sorafenib | autophagy related 5 | Homo sapiens |
| 2 | In summary, the formation of Atg5-deficient autophagosomes in response to sorafenib promotes the interaction of p62 with RIPK leading to cell death by necroptosis. | Sorafenib | autophagy related 5 | Homo sapiens |