Title : Sulfur and nitrogen mustards induce characteristic poly(ADP-ribosyl)ation responses in HaCaT keratinocytes with distinctive cellular consequences.

Pub. Date : 2016 Feb 26

PMID : 26383629






1 Functional Relationships(s)
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1 Since PARP inhibitors exhibit therapeutic potential to treat SM-related pathologies and to sensitize cancer cells for mustard-based chemotherapy, potential long-term effects of PARP inhibition on genomic stability and carcinogenesis should be carefully considered when pursuing such a strategy. Mustard Gas poly(ADP-ribose) polymerase 1 Homo sapiens