Pub. Date : 2015 Dec
PMID : 26350565
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The cholesterol metabolite 27-hydroxycholesterol regulates p53 activity and increases cell proliferation via MDM2 in breast cancer cells. | 27-hydroxycholesterol | MDM2 proto-oncogene | Homo sapiens |
| 2 | Furthermore, 27-OHC-induced proliferation was attenuated using either the p53 activator Tenovin-1 or the MDM2 inhibitor Nutlin-3 and Mdm2 siRNA. | 27-hydroxycholesterol | MDM2 proto-oncogene | Homo sapiens |
| 3 | Furthermore, 27-OHC-induced proliferation was attenuated using either the p53 activator Tenovin-1 or the MDM2 inhibitor Nutlin-3 and Mdm2 siRNA. | 27-hydroxycholesterol | MDM2 proto-oncogene | Homo sapiens |