Pub. Date : 2015 Sep 8
PMID : 26348154
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Three major structural and thermodynamic characteristics of the IT-state relative to the N-state in beta2m protein are detected that contribute to the increased amyloidogenic potential: (i) the disruption of the edge D-strand, (ii) the increased solvent-exposed hydrophobic interface, and (iii) the increased solvation free energy (less affinity toward solvent water). | Water | beta-2-microglobulin | Homo sapiens |