Pub. Date : 2016 Feb
PMID : 26346170
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 14-3-3sigma, HMGB1, and XPA were preferentially expressed in cisplatin-resistant SLMT-1 cells when compared to those more sensitive to cisplatin. | Cisplatin | high mobility group box 1 | Homo sapiens |
| 2 | In ESCC patients with poor response to cisplatin-based chemoradiation, their pre-treatment tumors expressed higher expression of HMGB1 than those with response to such treatment. | Cisplatin | high mobility group box 1 | Homo sapiens |
| 3 | In summary, our results demonstrate that 14-3-3sigma induces cisplatin resistance in ESCC cells and that 14-3-3sigma-mediated cisplatin resistance involves DNA repair molecules HMGB1 and XPA. | Cisplatin | high mobility group box 1 | Homo sapiens |