Title : N-acetyl cysteine protects human oral keratinocytes from Bis-GMA-induced apoptosis and cell cycle arrest by inhibiting reactive oxygen species-mediated mitochondrial dysfunction and the PI3K/Akt pathway.

Pub. Date : 2015 Dec

PMID : 26343756






2 Functional Relationships(s)
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1 N-acetyl cysteine protects human oral keratinocytes from Bis-GMA-induced apoptosis and cell cycle arrest by inhibiting reactive oxygen species-mediated mitochondrial dysfunction and the PI3K/Akt pathway. Acetylcysteine AKT serine/threonine kinase 1 Homo sapiens
2 We found that Bis-GMA inhibited the phosphorylation of Akt, whereas the amount of phosphorylated Akt was reverted to the control level in the presence of NAC. Acetylcysteine AKT serine/threonine kinase 1 Homo sapiens