Title : Dexamethasone-induced cell death is restricted to specific molecular subgroups of multiple myeloma.

Pub. Date : 2015 Sep 29

PMID : 26323097






1 Functional Relationships(s)
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1 We demonstrated that the pro-death effect of dexamethasone is related to the genetic heterogeneity of MM because sensitive cell lines were restricted to MAF and MMSET signature subgroups, whereas all CCND1 cell lines (n = 10) were resistant to dexamethasone. Dexamethasone MAF bZIP transcription factor Homo sapiens