Protein Name MAF bZIP transcription factor
Organism Homo sapiens
Gene ID 4094
Gene Symbol


UniProt O75444 (MAF_HUMAN), H3BP11 (H3BP11_HUMAN)
Relationships Total Number of functionally related compound(s) : 191
Total Number of Articles : 152

MAF bZIP transcription factor

Gene Summary

The protein encoded by this gene is a DNA-binding, leucine zipper-containing transcription factor that acts as a homodimer or as a heterodimer. Depending on the binding site and binding partner, the encoded protein can be a transcriptional activator or repressor. This protein plays a role in the regulation of several cellular processes, including embryonic lens fiber cell development, increased T-cell susceptibility to apoptosis, and chondrocyte terminal differentiation. Defects in this gene are a cause of juvenile-onset pulverulent cataract as well as congenital cerulean cataract 4 (CCA4). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2010]

  • transcription factor Maf
  • Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene
  • T lymphocyte c-maf long form
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