Pub. Date : 2015 Oct 4
PMID : 26286433
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Rational design of paraoxonase 1 (PON1) for the efficient hydrolysis of organophosphates. | Organophosphates | paraoxonase 1 | Homo sapiens |
| 2 | Rational design of paraoxonase 1 (PON1) for the efficient hydrolysis of organophosphates. | Organophosphates | paraoxonase 1 | Homo sapiens |
| 3 | A rational design of paraoxonase 1 based on molecular docking discovered H115W/T332S and I74F/H115W/T332S mutants exhibited a 40-fold increase in catalytic efficiency (kcat/Km) toward the hydrolysis of two toxic and popular organophosphates (diethyl-paraoxon and dimethyl-paraoxon). | Organophosphates | paraoxonase 1 | Homo sapiens |