Title : Enzyme sensitive, surface engineered nanoparticles for enhanced delivery of camptothecin.

Pub. Date : 2015 Oct 28

PMID : 26282096






1 Functional Relationships(s)
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1 Furthermore, The PEG layer would detach from the NPs due to the up-regulated extracellular MMP2 and MMP9 in tumors, resulting in the exposure of folate to enhance the cellular internalization via folate receptor mediated endocytosis, which accelerated the release rate of CPT in vivo. Folic Acid matrix metallopeptidase 9 Mus musculus