Title : Effects of dietary sodium restriction and potassium intake on cholesterol side-chain cleavage cytochrome P-450 and adrenodoxin mRNA levels.

Pub. Date : 1989

PMID : 2626031






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We studied the effect of dietary sodium restriction (3 weeks) and high potassium intake (7 days) on transcriptional regulation of cytochrome P-450 cholesterol side chain cleavage (P-450 scc) and adrenodoxin (Adx) in rat adrenal glands. Potassium cytochrome P450, family 11, subfamily a, polypeptide 1 Rattus norvegicus
2 These results thus indicate that both sodium depletion and high potassium intake in rats could act at the transcriptional level of P-450scc and Adx, two components of a rate-limiting step in steroidogenesis leading to aldosterone production. Potassium cytochrome P450, family 11, subfamily a, polypeptide 1 Rattus norvegicus