Pub. Date : 2015 Jan 1
PMID : 26257890
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NGAL-Siderocalin binds and sequesters the iron loaded bacterial siderophore enterochelin (Ent), defining the protein as an innate immune effector. | Iron | lipocalin 2 | Homo sapiens |
| 2 | While different catechols have been detected in human urine, they have not been directly purified from a biofluid and demonstrated to ligate iron with NGAL-Siderocalin. | Iron | lipocalin 2 | Homo sapiens |
| 3 | This paper describes a "natural products" approach to identify small molecules that mediate iron binding to NGAL-Siderocalin. | Iron | lipocalin 2 | Homo sapiens |
| 4 | Although catechol was a known NGAL-Siderocalin co-factor, our purification directly confirmed its presence in urine as well as its capacity to serve as an iron trap with NGAL-Siderocalin. | Iron | lipocalin 2 | Homo sapiens |