Title : Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis.

Pub. Date : 2016 May 5

PMID : 26257064






1 Functional Relationships(s)
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1 Increased metabolites, PTGS2 and PTGES protein levels were found in Skov3-ip1 and HeyA8 cells treated with norepinephrine (NE), and these changes were shown to be mediated by ADRB2 receptor signaling. Norepinephrine adrenoceptor beta 2 Homo sapiens