Title : High affinity α3β4 nicotinic acetylcholine receptor ligands AT-1001 and AT-1012 attenuate cocaine-induced conditioned place preference and behavioral sensitization in mice.

Pub. Date : 2015 Oct 15

PMID : 26256075






4 Functional Relationships(s)
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1 Among subtype-selective nAChR antagonists, the beta2-selective antagonist dihydrobetaerythroidine and alpha7 antagonist methyllycaconitine (MLA), but not MLA alone prevent behavioral sensitization to cocaine. methyllycaconitine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 Among subtype-selective nAChR antagonists, the beta2-selective antagonist dihydrobetaerythroidine and alpha7 antagonist methyllycaconitine (MLA), but not MLA alone prevent behavioral sensitization to cocaine. methyllycaconitine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
3 Among subtype-selective nAChR antagonists, the beta2-selective antagonist dihydrobetaerythroidine and alpha7 antagonist methyllycaconitine (MLA), but not MLA alone prevent behavioral sensitization to cocaine. methyllycaconitine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
4 Among subtype-selective nAChR antagonists, the beta2-selective antagonist dihydrobetaerythroidine and alpha7 antagonist methyllycaconitine (MLA), but not MLA alone prevent behavioral sensitization to cocaine. methyllycaconitine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus