Title : Identification and characterization of a novel CYP2C9 allelic variant in a warfarin-sensitive patient.

Pub. Date : 2015

PMID : 26255664






1 Functional Relationships(s)
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1 When expressed in yeast and insect cells, compared with wild-type enzyme, variant CYP2C9.60 exhibited lower protein expression capacity and showed significantly decreased metabolic activities for the hydroxylation of S-warfarin, tolbutamide and diclofenac. Tolbutamide cytochrome P450 family 2 subfamily C member 9 Homo sapiens