Title : Effects of structural modifications on the metal binding, anti-amyloid activity, and cholinesterase inhibitory activity of chalcones.

Pub. Date : 2015 Sep 28

PMID : 26248214






1 Functional Relationships(s)
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1 This work presents the design, synthesis, and biochemical evaluation of a series of chalcones, and assesses the relationship between their structures and their ability to bind metal ions and/or Abeta species, and inhibit AChE/BChE activity. Chalcones amyloid beta precursor protein Homo sapiens