Pub. Date : 2015
PMID : 26222138
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages. | Tetradecanoylphorbol Acetate | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 2 | NRF2 Signaling Negatively Regulates Phorbol-12-Myristate-13-Acetate (PMA)-Induced Differentiation of Human Monocytic U937 Cells into Pro-Inflammatory Macrophages. | Tetradecanoylphorbol Acetate | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 3 | In addition, PMA-inducible secretion of monocyte chemotactic protein 1 (MCP-1) was significantly high in NRF2-silenced U937. | Tetradecanoylphorbol Acetate | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 4 | Taken together, our results suggest that the NRF2 system functions to suppress PMA-stimulated U937 cell differentiation into pro-inflammatory macrophages and provide evidence that the ROS-PKCalpha-ERK-NFkB axis is involved in PMA-facilitated differentiation of NRF2-silenced U937 cells. | Tetradecanoylphorbol Acetate | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 5 | Taken together, our results suggest that the NRF2 system functions to suppress PMA-stimulated U937 cell differentiation into pro-inflammatory macrophages and provide evidence that the ROS-PKCalpha-ERK-NFkB axis is involved in PMA-facilitated differentiation of NRF2-silenced U937 cells. | Tetradecanoylphorbol Acetate | NFE2 like bZIP transcription factor 2 | Homo sapiens |