Title : Targeting Apoptosis and Multiple Signaling Pathways with Icariside II in Cancer Cells.

Pub. Date : 2015

PMID : 26221076






1 Functional Relationships(s)
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1 Icariside II has been found to induce apoptosis in various human cancer cell lines of different origin by targeting multiple signaling pathways including STAT3, PI3K/AKT, MAPK/ERK, COX-2/PGE2 and beta-Catenin which are frequently deregulated in cancers, suggesting that this collective activity rather than just a single effect may play an important role in developing Icariside II into a potential lead compound for anticancer therapy. baohuoside I catenin beta 1 Homo sapiens