Title : N-acetylcysteine Ameliorates the Erectile Dysfunction Caused by Chronic Intermittent Hypoxia in Rats: Partly Involvement of Endoplasmic Reticulum Stress.

Pub. Date : 2015 Oct

PMID : 26206453






2 Functional Relationships(s)
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1 RESULTS: Treatment with NAC inhibited apoptosis of penile tissue, the expressions of ERS-related products: BIP, CHOP, caspase12, and Bax, NO, and endothelial NOS. Acetylcysteine heat shock protein family A (Hsp70) member 5 Rattus norvegicus
2 CONCLUSION: Our results show that pre-CIH NAC administration ameliorates the ED following CIH partly by alleviating CIH-induced ERS and cell apoptosis via regulating the expressions of BIP, CHOP, caspase12, and Bax. Acetylcysteine heat shock protein family A (Hsp70) member 5 Rattus norvegicus