Title : Metformin effects on biochemical recurrence and metabolic signaling in the prostate.

Pub. Date : 2015 Nov

PMID : 26201966






2 Functional Relationships(s)
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1 When stratified by metformin use, IGF-1R remained significantly elevated (P = 0.01) in men with PCa detected whereas p-AMPK (P = 0.05) was elevated only in those without PCa. Metformin insulin like growth factor 1 receptor Homo sapiens
2 The finding of IGF-1R elevation in positive PNBs versus p-AMPK elevation in negative PNBs suggests altered metabolic pathway activation precipitated by metformin use. Metformin insulin like growth factor 1 receptor Homo sapiens