Title : Trastuzumab-mediated selective delivery for platinum drug to HER2-positive breast cancer cells.

Pub. Date : 2015 Oct

PMID : 26186063






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1 In this work, we described the design, synthesis, and characterization of conjugates combining trastuzumab with a platinum (IV) analog of oxaliplatin, in which the trastuzumab acted as an active targeting agent for HER2-positive cancer cells. Oxaliplatin erb-b2 receptor tyrosine kinase 2 Homo sapiens