Pub. Date : 2016 Nov
PMID : 26179931
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Morphine-induced locomotor sensitization produces structural plasticity in the mesocorticolimbic system dependent on CB1-R activity. | Morphine | cannabinoid receptor 1 (brain) | Mus musculus |
| 2 | Moreover, the lack of morphine-induced locomotor sensitization in CB1-R KO mice was accompanied by abnormal alterations in structural plasticity in the same mesocorticolimbic areas. | Morphine | cannabinoid receptor 1 (brain) | Mus musculus |
| 3 | These specific structural plasticity changes mediated by CB1-R activity seem necessary for the normal progression of morphine-induced locomotor sensitization and could play a critical role in the addictive process. | Morphine | cannabinoid receptor 1 (brain) | Mus musculus |