Title : Berberine inhibits tumor necrosis factor-α-induced expression of inflammatory molecules and activation of nuclear factor-κB via the activation of AMPK in vascular endothelial cells.

Pub. Date : 2015 Oct

PMID : 26166377






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Berberine inhibits tumor necrosis factor-alpha-induced expression of inflammatory molecules and activation of nuclear factor-kappaB via the activation of AMPK in vascular endothelial cells. Berberine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 In conclusion, the results of the present study indicated that berberine inhibits the TNF-alpha-induced expression of ICAM-1 and MCP-1, and the activation of NF-kappaB in HAECs in vitro, possibly through the AMPK-dependent pathway. Berberine protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens