Pub. Date : 2015 Oct
PMID : 26148936
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Silencing TRAF3IP2 blunted Aldo-induced IKKbeta, p65, JNK, and c-Jun activation, IL-18, IL-6 and CT-1 upregulation, and cardiomyocyte hypertrophy. | Aldosterone | interleukin 6 | Mus musculus |
| 2 | In isolated adult mouse cardiac fibroblasts (CF), Aldo stimulated TRAF3IP2-dependent IL-18 and IL-6 production, CTGF, collagen I and III expression, MMP2 activation, and proliferation and migration. | Aldosterone | interleukin 6 | Mus musculus |