Title : Apocynin attenuates cholesterol oxidation product-induced programmed cell death by suppressing NF-κB-mediated cell death process in differentiated PC12 cells.

Pub. Date : 2015 Oct

PMID : 26122972






1 Functional Relationships(s)
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1 7-Ketocholesterol caused an increase in the levels of cytosolic and nuclear NF-kappaB p65, cytosolic NF-kappaB p50 and cytosolic phospho-IkappaB-alpha, which was inhibited by the addition of 0.5 muM Bay11-7085 (an inhibitor of NF-kappaB activation). 7-ketocholesterol synaptotagmin 1 Rattus norvegicus