Protein Name ferrochelatase
Organism Homo sapiens
Gene ID 2235
Gene Symbol


UniProt P22830 (HEMH_HUMAN), Q7KZA3 (Q7KZA3_HUMAN), A0A499FJN5 (A0A499FJN5_HUMAN)
Relationships Total Number of functionally related compound(s) : 212
Total Number of Articles : 357


Gene Summary

The protein encoded by this gene is localized to the mitochondrion, where it catalyzes the insertion of the ferrous form of iron into protoporphyrin IX in the heme synthesis pathway. Mutations in this gene are associated with erythropoietic protoporphyria. Two transcript variants encoding different isoforms have been found for this gene. A pseudogene of this gene is found on chromosome 3.[provided by RefSeq, May 2010]

  • ferrochelatase, mitochondrial
  • heme synthase
  • heme synthetase
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