Title : Effects of nicotine on a rat model of early stage osteoarthritis.

Pub. Date : 2015

PMID : 26097542






2 Functional Relationships(s)
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1 Nicotine treatment ameliorated cartilage destruction, promoted matrix production, reduced the serum level of TNF-alpha and the expression of TNF-alpha in the synovial tissue, and increased the expression of alpha7nAChR in the synovial tissue in the rat model of early stage OA. Nicotine tumor necrosis factor Rattus norvegicus
2 Nicotine treatment ameliorated cartilage destruction, promoted matrix production, reduced the serum level of TNF-alpha and the expression of TNF-alpha in the synovial tissue, and increased the expression of alpha7nAChR in the synovial tissue in the rat model of early stage OA. Nicotine tumor necrosis factor Rattus norvegicus