Title : Modulation of Insulin Sensitivity of Hepatocytes by the Pharmacological Downregulation of Phospholipase D.

Pub. Date : 2015

PMID : 26089893






1 Functional Relationships(s)
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1 Inhibition of PLD by a general antagonist (1-butanol) or specific inhibitor, halopemide, or N-hexanoylsphingosine, or by cellular ceramides accumulated in doxorubicin-treated hepatocytes decreased insulin-stimulated glucose metabolism. Doxorubicin glycosylphosphatidylinositol specific phospholipase D1 Homo sapiens