Protein Name eukaryotic translation elongation factor 1 alpha 1
Organism Homo sapiens
Gene ID 1915
Gene Symbol


UniProt P68104 (EF1A1_HUMAN), Q6IPS9 (Q6IPS9_HUMAN)
Relationships Total Number of functionally related compound(s) : 225
Total Number of Articles : 267

eukaryotic translation elongation factor 1 alpha 1

Gene Summary

This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008]

  • elongation factor 1-alpha 1
  • CTCL tumor antigen
  • EF-1-alpha-1
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