Pub. Date : 2015 Jun
PMID : 26062410
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | METHODS: Following 24-hour treatment with various concentrations of chemerin (0, 10, 100) ng/mL and 30-minute insulin stimulation in C2C12 cells, the glucose uptake was evaluated using a fluorescence microplate reader. | Glucose | retinoic acid receptor responder (tazarotene induced) 2 | Mus musculus |
| 2 | RESULTS: Chemerin inhibited the glucose uptake of C2C12 cells in a dose-dependent manner, concomitant with the increases of IL-6, IL-8, TNF-alpha levels. | Glucose | retinoic acid receptor responder (tazarotene induced) 2 | Mus musculus |
| 3 | However, pretreatment with NF-kappaB blocker PDTC significantly abated the inhibitory effect of chemerin on glucose uptake, and also obviously decreased the levels of IL-6, IL-8 and TNF-alpha induced by chemerin. | Glucose | retinoic acid receptor responder (tazarotene induced) 2 | Mus musculus |