Title : Characterization of interactions and pharmacophore development for DFG-out inhibitors to RET tyrosine kinase.

Pub. Date : 2015 Jul

PMID : 26044359






1 Functional Relationships(s)
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1 Abt-348, Birb-796, Motesanib and Sorafenib are DFG-out multi-kinase inhibitors that have been reported to inhibit RET activity with good IC50 values. motesanib diphosphate ret proto-oncogene Homo sapiens