Title : Pharmacological inhibition of NADPH oxidase protects against cisplatin induced nephrotoxicity in mice by two step mechanism.

Pub. Date : 2015 Sep

PMID : 26032634






1 Functional Relationships(s)
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1 Tubular cell death by cisplatin led to pro-inflammatory response by production of TNFalpha and IL1beta followed by leukocyte/neutrophil infiltration which resulted in new wave of ROS involving more NADPH oxidases. Cisplatin tumor necrosis factor Mus musculus