Pub. Date : 2015
PMID : 26030092
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In a previous study we showed that stathmin increases vinblastine (VLB) binding to tubulin, and that conversely VLB increases stathmin binding to tubulin. | Vinblastine | stathmin 1 | Homo sapiens |
2 | Taken together with the previous study using vinblastine, our results suggest that stathmin can be seen as a modulator of MTA activity and binding to tubulin, providing molecular explanation for multiple previous cellular and in vivo studies showing that stathmin expression level affects MTAs efficiency. | Vinblastine | stathmin 1 | Homo sapiens |
3 | Taken together with the previous study using vinblastine, our results suggest that stathmin can be seen as a modulator of MTA activity and binding to tubulin, providing molecular explanation for multiple previous cellular and in vivo studies showing that stathmin expression level affects MTAs efficiency. | Vinblastine | stathmin 1 | Homo sapiens |