Title : SLCO1B1 polymorphism markedly affects the pharmacokinetics of lovastatin acid.

Pub. Date : 2015 Aug

PMID : 26020121






1 Functional Relationships(s)
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1 CONCLUSION: SLCO1B1*5/*15 and *15/*15 genotypes markedly increase the exposure to active lovastatin acid, but have no significant effect on lovastatin lactone, similar to their effects on simvastatin and simvastatin acid. simvastatin acid solute carrier organic anion transporter family member 1B1 Homo sapiens