Title : MCL-1 Is a Key Determinant of Breast Cancer Cell Survival: Validation of MCL-1 Dependency Utilizing a Highly Selective Small Molecule Inhibitor.

Pub. Date : 2015 Aug

PMID : 26013319






1 Functional Relationships(s)
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1 In the present study, we identify breast cancer cell lines that depend upon MCL-1 for survival and subsequently determine the mechanism of apoptosis mediated by the MCL-1 selective inhibitor A-1210477. A-1210477 MCL1 apoptosis regulator, BCL2 family member Homo sapiens