Title : Chronic Anatabine Treatment Reduces Alzheimer's Disease (AD)-Like Pathology and Improves Socio-Behavioral Deficits in a Transgenic Mouse Model of AD.

Pub. Date : 2015

PMID : 26010758






1 Functional Relationships(s)
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1 We found that anatabine reduces the activation of STAT3 and NFkappaB in the vicinity of Abeta deposits in Tg PS1/APPswe mice resulting in a reduction of the expression of some of their target genes including Bace1, iNOS and Cox-2. anatabine nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 Mus musculus