Title : Discovery of biphenyl-aryl ureas as novel VEGFR-2 inhibitors. Part 4: exploration of diverse hinge-binding fragments.

Pub. Date : 2015 Jul 1

PMID : 25982075






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 SAR study suggested that incorporation of 3-trifluoromethyl and methylamine carbonyl on terminal pyridine could improve VEGFR-2 inhibitory activity. pyridine kinase insert domain receptor Homo sapiens