Protein Name tet methylcytosine dioxygenase 2
Organism Homo sapiens
Gene ID 54790
Gene Symbol

TET2

UniProt Q6N021 (TET2_HUMAN), A0A024RDF7 (A0A024RDF7_HUMAN), A0A158SIU0 (A0A158SIU0_HUMAN)
Relationships Total Number of functionally related compound(s) : 128
Total Number of Articles : 298
Description

tet methylcytosine dioxygenase 2

Gene Summary

The protein encoded by this gene is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. The encoded protein is involved in myelopoiesis, and defects in this gene have been associated with several myeloproliferative disorders. Two variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011]

synonyms
  • methylcytosine dioxygenase TET2
  • probable methylcytosine dioxygenase TET2
  • ten-eleven translocation 2
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Properties