Title : Inositol hexaphosphate suppresses growth and induces apoptosis in HT-29 colorectal cancer cells in culture: PI3K/Akt pathway as a potential target.

Pub. Date : 2015

PMID : 25973024






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 The mRNA and protein expression of PI3K and Akt decreased in the groups treated with IP6, and IP6 inhibited the phosphorylation of Akt (pAkt), whereas increased the expression of its downstream effector, caspase-9. Phytic Acid caspase 9 Homo sapiens
2 The mRNA and protein expression of PI3K and Akt decreased in the groups treated with IP6, and IP6 inhibited the phosphorylation of Akt (pAkt), whereas increased the expression of its downstream effector, caspase-9. Phytic Acid caspase 9 Homo sapiens