Title : Antifibrotic effect of lysophosphatidic acid receptors LPA1 and LPA3 antagonist on experimental murine scleroderma induced by bleomycin.

Pub. Date : 2015 Sep

PMID : 25959255






1 Functional Relationships(s)
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1 Additionally, RT-PCR analysis showed that the mRNA levels of TGF-beta1, CTGF, MIP-1alpha, IFN-gamma and collagen alpha1(I) were significantly decreased in both the 1-mg/kg and 10-mg/kg groups of the Ki16425-treated mice compared with those in the controls. 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid transforming growth factor, beta 1 Mus musculus